Artificial insemination, as one of the most advanced assisted reproductive technologies, plays an important role in solving the problem of infertility in couples. However, this technology is associated with numerous jurisprudential and legal issues that require careful and analytical examination. In Iran, considering the influence of jurisprudential and Islamic principles on the legal system, examining this issue is of great importance. This article examines the jurisprudential and legal aspects of artificial insemination in Iran. This research shows that artificial insemination between couples is permissible from a jurisprudential and legal perspective, but the use of a third party's sperm or egg is associated with numerous jurisprudential and legal problems. Using an analytical method and examining jurisprudential and legal sources, this article seeks to answer the question: How can artificial insemination be regulated in Iran in a way that is both consistent with jurisprudential principles and minimizes its legal and ethical problems? The findings of this study show that the lack of clear and precise laws regarding artificial insemination can lead to social, legal, and ethical problems. Therefore, there is a need to formulate more precise laws and increasing public awareness in this field.