One of the most important effects of technology in the current era is artificial intelligence. One of the most important fields of using this new technology is the field of crime detection and criminal investigations. Artificial intelligence uses mechanisms for this purpose that have a very low error rate and help crime detection teams as well as judicial and police authorities in a very effective way. The importance of artificial intelligence, especially in some specific types of crimes, can have far more applications. Examples of these crimes are serial murders, which, due to their nature, characteristics, and effects, are crimes that seriously endanger the psychological safety of the society, and the pursuit and arrest of the perpetrators, as well as the prevention of their repetition, is an inevitable necessity. In some police organizations, artificial intelligence has been used for several years to track down and arrest serial killers, including the crime detection police in the United States. Considering the necessity of exploiting the experiences of other legal and judicial systems to solve the problems in the country, in this article, an attempt has been made to develop a set of mechanisms based on artificial intelligence technology, and with their help, the process of pursuing murderers implemented a serial and currently, these methods are used by the serial murder detection department in the United States police organization to be introduced.